OsNRAMP2 Mediates Preferential Manganese Distribution and Remobilization to Developing Tissues in Rice

Summary statement This study reveals that the vacuolar membrane transporter OsNRAMP2 is essential for manganese (Mn) homeostasis in rice. It facilitates the export of Mn from vacuoles in roots and nodes, enabling the remobilization and preferential distribution of Mn to young leaves and grains. Loss of OsNRAMP2 function disrupts this process, leading to Mn accumulation in roots and nodes, severe Mn deficiency in developing tissues and significantly reduced yield.