Metabolic Pathways of Polycyclic Aromatic Hydrocarbons and Functional Regulation of Proteins

Background: Polycyclic aromatic hydrocarbons (PAHs) are a major class of organic pollutants that are widely distributed in the environment and cause human disease and harm the ecological environment. Objective: The principle processes for their successful removal from the environment (such as soil, sediment, or water) are currently believed to be microbial transformation and degradation. Results: Studying the metabolic pathways involving PAHs and identifying the functional regulation of proteins involved in biodegradation will lead to their more effective and controllable bioremediation with the application of degrading bacteria. Keywords: Polycyclic Aromatic Hydrocarbons (PAHs), metabolic pathways, functional regulation of proteins, proteomic technology, iTRAQ, biodegradation pathway.