伊库利珠单抗
医学
非典型溶血尿毒综合征
中止
内科学
肾功能
胃肠病学
血栓性微血管病
系数H
药品
补体系统
抗体
免疫学
血小板
入射(几何)
复合杂合度
基因分型
儿科
回顾性队列研究
基因检测
替代补体途径
作者
Y X Zhang,P Liu,Y J Liu,Y L Li,G H Cao,M Tian,C H Liu
出处
期刊:PubMed
日期:2026-05-02
卷期号:64 (5): 545-550
标识
DOI:10.3760/cma.j.cn112140-20251117-01035
摘要
Eculizumab can significantly improve renal function, reduce the incidence of renal failure in the treatment of pediatric atypical hemolytic uremic syndrome and is associated with high safety and few adverse reactions. The decision on treatment discontinuation can be made following the physician-patient shared decision-making model, with the timing reasonably chosen based on the patient's clinical condition and family financial status.
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