荧光素酶
萤火虫协议
非竞争性抑制
化学
生物化学
系列（地层学）
酶
药理学
生物
基因
转染
动物
古生物学
作者
Haixiu Bai,Wang Chen,Wu Wen,Zhao Ma,Huateng Zhang,Tianyu Jiang,Tianchao Zhang,Yubin Zhou,Lüpei Du,Yuemao Shen,Minyong Li
出处
期刊：RSC Advances
[Royal Society of Chemistry]
日期：2015-01-01
卷期号：5 (78): 63450-63457
被引量：7
摘要
A series of 2-phenylnaphthalenes as firefly luciferase inhibitors are reported. The most potent compound 5 showed good systemic inhibition in transgenic mice. Kinetic assay indicated 5 is competitive for aminoluciferin and noncompetitive for ATP.
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