Microwave-assisted intramolecular reductive Heck in aqueous medium: Synthesis of 3,3′-Disubstituted heterocyclic compounds

Heterocyclic products have been accomplished using microwave-assisted [Pd]-catalyzed intramolecular reductive Heck coupling. The protocol found suitable in delivering indolines, oxindoles, and dihydrobenzofurans. Notably, the process was successful in sole aqueous medium and furnished the products bearing a quaternary carbon center.