SbCl3 Initiated Aerobic Phosphorylation of sp3 C−H Bond: A Facile Approach to α‐Phosphorylated Tetrahydroisoquinolines

An aerobic phosphorylation of N-aryltetrahydroisoquinolines was realized by SbCl3 initiated sp3 C-H bond functionalization, providing a series of α-aminophosphonates in high yields. This work reveals that SbCl3 /O2 is an efficient and facile catalyst system to enable the aerobic C-H functionalization, and antimony containing reagents might be potentially applied to more general transformations.