Ring opening of cyclopropyl ketones with 1,3-diketones for the synthesis of 1,6-diketone derivatives

A series of 1,6-diketone derivatives were prepared by first copper (II) trifluoromethanesulfonate catalysed ring-opening of cyclopropyl ketones with 1,3-diketones followed by DBU-promoted retro-Claisen-type reactions. The acyclic 1,3-diketones selectively worked as carbon-nucleophiles to add to the donor–acceptor cyclopropanes. The ring-opening products underwent CC bond cleavage to afford 1,6-diketone derivatives concisely.