肝细胞癌
表观遗传学
免疫疗法
癌症研究
医学
免疫学
生物
免疫系统
遗传学
基因
作者
Yalin Tu,Haoran Wu,Chengpeng Zhong,Yan Liu,Zhewen Xiong,Siyun Chen,Jing Wang,Patrick Pak-Chun Wong,Weiqin Yang,Zhixian Liang,Jiahuan Lu,Shufen Chen,Lingyun Zhang,Yu Feng,Willis Wai-Yiu Si-Tou,Baoyi Yin,Yingnan Lin,Jianxin Liang,Liying Liang,Joaquim S. L. Vong
出处
期刊：Gut
[BMJ]
日期：2024-11-01
卷期号：: gutjnl-332281
被引量：13
标识
DOI：10.1136/gutjnl-2024-332281
摘要
Genomic screening uncovered interferon-gamma (IFNγ) pathway defects in tumours refractory to immune checkpoint blockade (ICB). However, its non-mutational regulation and reversibility for therapeutic development remain less understood.
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