早晨
医学
慢性阻塞性肺病
恶化
观察研究
入射(几何)
叙述性评论
肺病
物理疗法
日常生活活动
疾病
内科学
重症监护医学
光学
物理
作者
Maochun Wu,Zequan Wang,Manman Li,Kun Li
标识
DOI:10.1177/0193945917705132
摘要
Daily symptom variability refers to the fluctuation of chronic obstructive pulmonary disease (COPD) symptoms over the day. Although most clinicians can describe the day-to-day variation in symptoms experienced by patients with COPD, little has been done to quantify the variability. This review aims to synthesize evidence of daily symptom variability among patients with stable COPD. Of the 325 potentially relevant articles that were retrieved, 11 observational articles were finally included in the review. Patients with stable COPD commonly experience daily symptom variability, with morning being the most troublesome time of day, followed by night. Morning symptoms had a significant effect on morning routines or daily activities, and night-time symptoms affected the sleep quality of patients. In comparison with patients without symptom variability, patients with morning/night-time symptoms or symptom variability exhibited poorer health status as well as greater disease severity and incidence of exacerbation.
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