医学
牙周炎
内科学
优势比
慢性牙周炎
逻辑回归
糖尿病
风险因素
内分泌学
作者
Mario Romandini,Gioele Gioco,Giorgio Perfetti,Giorgio Deli,Edoardo Staderini,Andreina Laforì
摘要
Abstract Aim Due to its potential to influence systemic inflammation and oxidative stress, and to predispose to bacterial infections, sleep duration could potentially be a risk factor for periodontitis. The aim of this cross‐sectional study was to evaluate if there was in 2012 an association between periodontitis and sleep duration in a representative sample of the South Korean population. Materials and Methods A total of 5812 subjects representative of 39.4 million of adults were examined. Multivariate logistic regressions were applied controlling for age, gender, education, smoking status, alcoholism and consumption frequency of coffee, tea, chocolate and red wine. Results Compared to the group sleeping ≤5 h/day, the adjusted odds ratios for periodontitis prevalence defined as Community Periodontal Index ( CPI ) = 4 were OR = 2.46 (95% CI : 1.20–5.06) in the 6 h/day sleepers group, OR = 2.66 (95% CI : 1.35–5.25) in the 7 h/day sleepers group, OR = 2.29 (95% CI : 1.13–4.63) in the 8 h/day sleepers group and OR = 4.27 (95% CI : 1.83–9.97) in the ≥9 h/day sleepers group. The association has shown to be highlighted in middle‐aged people, females, non‐smokers, lower educated, with lower lead and higher cadmium blood levels and with higher carotene dietary intake ones and to be partially mediated by lipid profile alterations, diabetes, serum Vitamin D levels and WBC count. Conclusions A novel, direct and independent association between sleep duration and the prevalence of periodontitis was found. However, it needs to be investigated how the factors influencing the sleep duration affect this association.
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