Dietary and Lifestyle Risk Factors Associated with Incident Kidney Stones in Men and Women

No AccessJournal of UrologyAdult Urology1 Oct 2017Dietary and Lifestyle Risk Factors Associated with Incident Kidney Stones in Men and Women Pietro Manuel Ferraro, Eric N. Taylor, Giovanni Gambaro, and Gary C. Curhan Pietro Manuel FerraroPietro Manuel Ferraro Division of Nephrology, Fondazione Policlinico Universitario A. Gemelli, Catholic University of the Sacred Heart, Rome, Italy , Eric N. TaylorEric N. Taylor Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts Division of Nephrology and Transplantation, Maine Medical Center, Portland, Oregon , Giovanni GambaroGiovanni Gambaro Division of Nephrology, Fondazione Policlinico Universitario A. Gemelli, Catholic University of the Sacred Heart, Rome, Italy , and Gary C. CurhanGary C. Curhan Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts Renal Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts View All Author Informationhttps://doi.org/10.1016/j.juro.2017.03.124AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: Several dietary and lifestyle factors are associated with a higher risk of kidney stones. We estimated the population attributable fraction and the number needed to prevent for modifiable risk factors, including body mass index, fluid intake, DASH (Dietary Approaches to Stop Hypertension) style diet, dietary calcium intake and sugar sweetened beverage intake. Materials and Methods: We used data on the HPFS (Health Professionals Follow-Up Study) cohort and the NHS (Nurses' Health Study) I and II cohorts. Information was obtained from validated questionnaires. Poisson regression models adjusted for potential confounders were used to estimate the association of each risk factor with the development of incident kidney stones and calculate the population attributable fraction and the number needed to prevent. Results: The study included 192,126 participants who contributed a total of 3,259,313 person-years of followup, during which an incident kidney stone developed in 6,449 participants. All modifiable risk factors were independently associated with incident stones in each cohort. The population attributable fraction ranged from 4.4% for a higher intake of sugar sweetened beverages to 26.0% for a lower fluid intake. The population attributable fraction for all 5 risk factors combined was 57.0% in HPFS, 55.2% in NHS I and 55.1% in NHS II. The number needed to prevent during 10 years ranged from 67 for lower fluid intake to 556 for lower dietary calcium intake. 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Google Scholar © 2017 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited byAssimos D (2020) Re: Effect of Water Composition and Timing of Ingestion on Urinary Lithogenic Profile in Healthy Volunteers: A Randomized Crossover TrialJournal of Urology, VOL. 204, NO. 6, (1374-1374), Online publication date: 1-Dec-2020.Assimos D (2020) Re: Risk of Kidney Stones: Influence of Dietary Factors, Dietary Patterns, and Vegetarian-Vegan DietsJournal of Urology, VOL. 204, NO. 3, (612-612), Online publication date: 1-Sep-2020.Shu X, Calvert J, Cai H, Xiang Y, Li H, Zheng W, Shu X and Hsi R (2019) Plant and Animal Protein Intake and Risk of Incident Kidney Stones: Results from the Shanghai Men's and Women's Health StudiesJournal of Urology, VOL. 202, NO. 6, (1217-1223), Online publication date: 1-Dec-2019.Ferraro P, Ticinesi A, Meschi T, Rodgers A, Di Maio F, Fulignati P, Borghi L and Gambaro G (2018) Short-Term Changes in Urinary Relative Supersaturation Predict Recurrence of Kidney Stones: A Tool to Guide Preventive Measures in UrolithiasisJournal of Urology, VOL. 200, NO. 5, (1082-1087), Online publication date: 1-Nov-2018.Smith J (2017) This Month in Adult UrologyJournal of Urology, VOL. 198, NO. 4, (715-716), Online publication date: 1-Oct-2017. Volume 198Issue 4October 2017Page: 858-863 Advertisement Copyright & Permissions© 2017 by American Urological Association Education and Research, Inc.Keywordsdiet, food, and nutritionlife stylerisk reduction behaviorkidney calculirisk factorsMetricsAuthor Information Pietro Manuel Ferraro Division of Nephrology, Fondazione Policlinico Universitario A. Gemelli, Catholic University of the Sacred Heart, Rome, Italy More articles by this author Eric N. Taylor Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts Division of Nephrology and Transplantation, Maine Medical Center, Portland, Oregon More articles by this author Giovanni Gambaro Division of Nephrology, Fondazione Policlinico Universitario A. Gemelli, Catholic University of the Sacred Heart, Rome, Italy More articles by this author Gary C. Curhan Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts Renal Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts Financial interest and/or other relationship with UpToDate, Decibel Therapeutics and Allena Pharmaceuticals. More articles by this author Expand All Advertisement PDF downloadLoading ...