Pd‐Catalyzed Tandem Coupling Reaction of 2‐gem‐Dibromovinylanilines and N‐Tosylhydrazones to Construct 2‐(1‐phenylvinyl)‐indoles

Abstract A novel palladium(0)‐catalyzed intermolecular coupling reaction of 2‐ gem ‐dibromovinylanilines and N ‐tosylhydrazones was reported to construct 2‐(1‐phenylvinyl)‐indoles efficiently. The indole bearing 1, 1‐disubstituted alkenes were obtained in one step with short reaction time, in high yields and broad substrate scope. The formed indole derivates could be easily transformed into much more valuable molecules. magnified image