腹膜透析
腹膜炎
腹膜平衡试验
医学
内科学
腹膜
胃肠病学
比例危险模型
外科
超滤(肾)
连续不卧床腹膜透析
色谱法
化学
作者
Y.-C. Chou,Yung‐Tai Chen,Jinn-Yang Chen,Der Cherng Tarng,Chih‐Ching Lin,Szu‐Yuan Li
出处
期刊:Membranes
[MDPI AG]
日期:2022-02-28
卷期号:12 (3): 276-276
标识
DOI:10.3390/membranes12030276
摘要
The peritoneal equilibration test (PET) is a semi-quantitative measurement that characterizes the rate of transfer of solutes and the water transfer rate across the peritoneum in patients treated with peritoneal dialysis (PD). The results of the PET are used to maximize daily peritoneal ultrafiltration and solute clearances. Previous studies have shown that high transport status is associated with ultrafiltration failure, malnutrition, and reduced survival; however, the way in which peritoneum transport characteristics affect peritonitis risk is unknown. In the current cohort study, we recruited 898 incident-PD patients and used intention-to-treat analysis to test if baseline PET affected the subsequent 3-year peritonitis rate. Among all recruited PD patients, 308 (34.2%) developed peritonitis within three years. Multivariate Cox regression analysis showed that the high-transport group has the greatest peritonitis risk (HR 1.98, 95% CI: 1.08-3.62) even after an adjustment for demographics, comorbid diseases, and biochemical measurements. We concluded that a baseline high peritoneal membrane transport rate is an independent risk factor for peritonitis in incident PD patients.
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