A comprehensive review on polysaccharides with hypolipidemic activity: Occurrence, chemistry and molecular mechanism

褐藻糖胶 化学 多糖 保健品 生物化学 生物
作者
Pratap Kalita,Abdul Baquee Ahmed,Saikat Sen,Raja Chakraborty
出处
期刊:International Journal of Biological Macromolecules [Elsevier]
卷期号:206: 681-698 被引量:65
标识
DOI:10.1016/j.ijbiomac.2022.02.189
摘要

Currently, research on natural products is facing challenging future in various aspects. A large group of natural polysaccharides such as β-glucan, cellulose, hemicellulose, chitin, pectin, agaropectin, heteroglycans, lignins, hydrocolloids, homopolysaccharides, heteropolysaccharides were studied extensively for their various therapeutical potential. Several research works have already demonstrated those polysaccharides has tremendous health benefits, and found to exhibit anticancer, antiviral, immunomodulatory, antimicrobial, anticoagulant, anti-inflammatory, antidiabetic, antioxidant and antitumor activities. Different mushroom, plant, fungus, algae, vegetables, microalgae etc. are some important source of several polysaccharide macromolecules such as glucans, ulvan A, ulvan B, fucoidan, rhamnan sulfate, laminarin sulfate, agar, alginate, heteroglycans. Earlier research work demonstrated that natural polysaccharides have the highest ability to carry biological properties along with some biopolymers like as proteins and nucleic acids due to their structural variability. The preventive effect of these biomacromolecules was extensively studied, especially their beneficial effect on chronic metabolic conditions like dyslipidemia and related disorders. Dyslipidemia is a serious metabolic disorder associated with coronary heart disease, coronary artery diseases, hypercholesterolemia, atherosclerosis, etc. Dietary natural polysaccharides could play an important role in the management and prevention of dyslipidemia. Polysaccharides from natural sources mainly sulfated polysaccharides exhibited predominant lipid-lowering and cholesterol-lowering activities through different mechanisms. Polysaccharides isolated from different edible plants, vegetables, plant, algae, mushroom with higher biological activities, particularly hypolipidemic activity were highlighted in this paper, in a way for their futuristic therapeutic application. This review aims to comprehensively discuss overall advances in hypolipidemic activity of polysaccharides, including their sources, structural characteristic and chemistry, biological activity and their probable mode of action.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
6秒前
6秒前
水星完成签到 ,获得积分10
21秒前
西陆完成签到,获得积分10
21秒前
木偶人完成签到,获得积分10
23秒前
Elio完成签到 ,获得积分10
27秒前
灵巧的初蝶完成签到,获得积分10
28秒前
小芳芳完成签到 ,获得积分10
28秒前
公子扶腰完成签到,获得积分10
29秒前
向建完成签到 ,获得积分10
31秒前
xyl_507完成签到 ,获得积分0
32秒前
支雨泽完成签到,获得积分10
33秒前
永安完成签到 ,获得积分0
35秒前
方方完成签到 ,获得积分10
39秒前
鱼儿忆流年完成签到 ,获得积分10
40秒前
yzy完成签到,获得积分10
43秒前
小潘完成签到 ,获得积分10
43秒前
善学以致用应助mm采纳,获得10
52秒前
内向东蒽完成签到 ,获得积分10
53秒前
57秒前
PLT完成签到,获得积分10
58秒前
doctorw完成签到 ,获得积分10
59秒前
DAHove完成签到 ,获得积分10
1分钟前
mm应助文件撤销了驳回
1分钟前
方好完成签到,获得积分10
1分钟前
刀笔吏完成签到,获得积分10
1分钟前
吃吃货完成签到 ,获得积分10
1分钟前
瑞曦完成签到 ,获得积分10
1分钟前
容容容完成签到 ,获得积分10
1分钟前
Grace159完成签到 ,获得积分10
1分钟前
zhangy559完成签到 ,获得积分10
1分钟前
yqcsysu完成签到 ,获得积分10
1分钟前
cjq完成签到,获得积分10
1分钟前
1分钟前
科研通AI2S应助科研通管家采纳,获得10
1分钟前
薰硝壤应助科研通管家采纳,获得10
1分钟前
一三二五七完成签到 ,获得积分0
1分钟前
Bella完成签到 ,获得积分10
1分钟前
不甜完成签到 ,获得积分10
1分钟前
orixero应助cripple采纳,获得10
1分钟前
高分求助中
좌파는 어떻게 좌파가 됐나:한국 급진노동운동의 형성과 궤적 2500
Sustainability in Tides Chemistry 1500
TM 5-855-1(Fundamentals of protective design for conventional weapons) 1000
Cognitive linguistics critical concepts in linguistics 800
Threaded Harmony: A Sustainable Approach to Fashion 799
Livre et militantisme : La Cité éditeur 1958-1967 500
氟盐冷却高温堆非能动余热排出性能及安全分析研究 500
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3052652
求助须知:如何正确求助?哪些是违规求助? 2709891
关于积分的说明 7418319
捐赠科研通 2354494
什么是DOI,文献DOI怎么找? 1246122
科研通“疑难数据库(出版商)”最低求助积分说明 605951
版权声明 595921