ECT/chlorpromazine combination versus chlorpromazine alone in acutely schizophrenic patients.

The response to ECT or no ECT at two levels of chlorpromazine was studied in a 2 × 2 factorial experiment on 60 acutely schizophrenic patients hospitalized for a period of 6 weeks. ECT enhanced the therapeutic response at the 300 mg level of chlorpromazine but neither of the ECT chlorpromazine combinations offered any significant therapeutic advantage over 500 mg of chlorpromazine.