医学
奎尼丁
普鲁卡因胺
洋地黄
心脏病学
麻醉
心动过速
心室颤动
硫利达嗪
内科学
心力衰竭
氯丙嗪
出处
期刊:JAMA
[American Medical Association]
日期:1986-08-01
卷期号:256 (5): 621-627
被引量:32
标识
DOI:10.1001/jama.256.5.621
摘要
THE ECTOPIC TACHYCARDIAS are currently treated by either vagal stimulation or drugs. The 3 most effective drugs are quinidine, procainamide hydrochloride, and the digitalis glycosides. When the ectopic mechanism drives the ventricles at rates above 160 per minute, cardiac output falls and coronary blood flow is compromised. This is most likely to occur with ventricular tachycardia which constitutes a serious cardiac emergency requiring immediate treatment. Frequently, however, the arrhythmia cannot be terminated promptly. Reversion with drugs generally involves a time-consuming biologic titration. Since it is impossible in any one patient to predict either the effective or the toxic dose, small increments of antiarrhythmic drugs are given at frequent intervals until a therapeutic end point is reached. The interval between doses is determined by the gravity of the patient's illness as well as by the rapidity of action of the particular agent. It may thus take minutes, days, or even weeks
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