Observation of the effect of methylcobalamin in the treatment of diabetic peripheral neuropathy

Objective To observe the effect of methylcobalamin for diabetic periferal neuropathy(DPU).Methods 80 patients with DPU were randomly divided into treament group and control group,40 cases of each.The treatment group was given methylcobalamin injection 1mg intravenous drip once a day,while patients in the control group was given danshen injection 250ml intravenous drip once a day.Continued 14 days for a course of treatment,and used for two courses.The nerve conductive velocity(NVC) of the tibial nerve and the common peroneal nerve were examined pre and post treatment,as well as hoffman reflex.Results After treatment for 4 weeks,there was a significant difference in MCV、SCV and hoffinan between pre and post treatment in the treatment group,The differences were statistically significant(P0.05),while no difference in the control group(P0.05).There was significant difference between the indicators of two groups(P0.05).Conclusion Methylcobalamin has good therapeutic effect in treating diabetic periferal neuropathy.