幻肢
幻肢痛
截肢
感觉
背根神经节
幻觉痛
物理医学与康复
神经科学
医学
外周神经系统
神经系统
生活质量(医疗保健)
中枢神经系统
背
心理学
外科
解剖
护理部
社会心理学
作者
Kassondra Collins,Hannah G. Russell,Patrick J. Schumacher,Katherine E. Robinson-Freeman,Ellen C. O’Conor,Kyla D. Gibney,Olivia Yambem,Robert W. Dykes,Robert S. Waters,Jack W. Tsao
摘要
Following amputation, most amputees still report feeling the missing limb and often describe these feelings as excruciatingly painful. Phantom limb sensations (PLS) are useful while controlling a prosthesis; however, phantom limb pain (PLP) is a debilitating condition that drastically hinders quality of life. Although such experiences have been reported since the early 16th century, the etiology remains unknown. Debate continues regarding the roles of the central and peripheral nervous systems. Currently, the most posited mechanistic theories rely on neuronal network reorganization; however, greater consideration should be given to the role of the dorsal root ganglion within the peripheral nervous system. This Review provides an overview of the proposed mechanistic theories as well as an overview of various treatments for PLP.
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