微量白蛋白尿
蛋白质组学
糖尿病肾病
医学
糖尿病
疾病
生物信息学
内科学
重症监护医学
内分泌学
生物
生物化学
基因
出处
期刊:Chin J Kidney Dis Invest(Electronic Edition)
日期:2018-08-28
卷期号:7 (4): 182-185
标识
DOI:10.3877/cma.j.issn.2095-3216.2018.04.010
摘要
Diabetic nephropathy (DN) is the most common microvascular complication of diabetes, and also an important cause for end-stage renal disease (ESRD). Microalbuminuria is not a reliable indicator for predicting the progression of DN. Looking for early biomarkers and investigating the mechanisms of renal early lesions in DN are currently the paramount missions. Proteomics technologies have developed rapidly in recent years, and proteomics research on urine, blood and kidney tissue of DN patients may provide new hope for early diagnosis and treatment of DN. This review summarized the major technologies of proteomics and its recent progress in DN.
Key words:
Diabetes mellitus; Diabetic nephropathy; Proteomics
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