伤口愈合
间充质干细胞
微泡
医学
疤痕
皮肤修复
增生性瘢痕
外体
病理
免疫学
生物
小RNA
生物化学
基因
作者
Jin Sun,Chenshuo Shi,D L Wang
出处
期刊:Chinese journal of burns
日期:2021-05-20
卷期号:37 (5): 495-500
被引量:1
标识
DOI:10.3760/cma.j.cn501120-20200410-00220
摘要
Skin is an important defense barrier of human body and one of the most vulnerable organs. Wounds are the result of damage to the integrity of skin. Chronic wounds and hypertrophic scar formation are the results of abnormal wound healing, and are also the clinical problems those need to be resolved urgently in the field of wound repair. In recent years, researchers have found that mesenchymal stem cells (MSCs) can promote wound healing, improve wound healing quality, and reduce scar formation. The therapeutic effect of MSCs may be derived from the exosomes derived from them. This paper reviews the research advances of exosomes derived from MSCs in wound healing and prevention and treatment of hypertrophic scars in recent years and looks up to the prospect for the clinical application.
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