干细胞
医学
疾病
干细胞疗法
诱导多能干细胞
生物
细胞疗法
遗传增强
再生医学
细胞生物学
癌症研究
作者
Shan Tang,Li Bai,Zhongping Duan,Sujun Zheng
出处
期刊:Current Stem Cell Research & Therapy
日期:2021-10-06
卷期号:16: 1-9
标识
DOI:10.2174/1574888x16666211006111556
摘要
Wilson disease (WD) is a copper excretion disorder, mainly caused by mutations in the ATP7B gene. Pharmacological therapies and liver transplantation are currently the main treatment methods for WD, but they face problems such as drug treatment compliance, adverse reactions, and shortage of liver donors. Stem cell therapy of WD may correct abnormal copper metabolism permanently, which is the focus of current research. In this review, we summarized the latest research on stem cells treatment for WD, as well as current challenges and future expectations.
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