抗真菌
核化学
抗氧化剂
化学
碳纤维
纳米技术
微生物学
材料科学
生物
生物化学
复合数
复合材料
作者
Parya Ezati,Jong‐Whan Rhim,Rahim Molaei,Ruchir Priyadarshi,Swarup Roy,Seungjae Min,Yeon Ho Kim,Seok‐Geun Lee,Sanghee Han
标识
DOI:10.1016/j.susmat.2022.e00397
摘要
Carbon dots are prepared using glucose as a carbon source (GCD) and doped with heteroatoms such as boron, sulfur, and nitrogen to enhance their functionality. FTIR and XPS results confirm doping of GCDs with heteroatoms, and their particle size is ~10 nm, as shown by TEM images. GCDs are very hydrophilic and stable in an aqueous solution, and nitrogen-doped GCD (NGCD) exhibits the highest polydispersity index of 0.274. The GCDs show excellent tunability of the PL emission with the variation in excitation wavelength. All the GCDs display excellent antioxidant function with the highest activity in the NGCD. The boron-doped GCD (BGCD) and sulfur-doped GCD (SGCD) exhibit more potent antibacterial activity against E. coli and Listeria monocytogenes . The NGCD is effective against both bacterial strains, showing the highest antibacterial activity. The NGCD exhibits potent antifungal activity against Ammophilus fumigatus , P. citrinum , C. albicans , and R. rubra , while the SGCD has a higher inhibitory effect on the growth of F. solani . Besides, more than 80% of the mouse fibroblast L929 cells are viable even when exposed to a high concentration of 500 μg/mL for 72 h, indicating low toxicity. • Heteroatom (N, S, and B) doped CDs were synthesized via hydrothermal method. • CDs exhibited excellent antioxidant activity. • Doping enhanced antibacterial and antifungal effect of CDs against various strains. • Prominent biocompatibility of CDs was confirmed by in-vitro cytotoxicity test.
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