髓系白血病
突变体
白血病
癌症研究
脆弱性(计算)
癌症
生物
免疫学
遗传学
基因
计算机科学
计算机安全
作者
Hyemin Lee,Zhuang Li,Boyi Gan
标识
DOI:10.1016/j.trecan.2023.04.011
摘要
Abstract
Resistance to FLT3 inhibition is a prevalent challenge in managing FLT3-mutant acute myeloid leukemia (AML). A recent study by Sabatier et al. discovered ferroptosis vulnerability in FLT3-mutant AML and they propose a promising therapeutic approach of combining FLT3 inhibitors with ferroptosis inducers for treating this type of cancer.
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