基因沉默
癌症研究
肺癌
HDAC1型
医学
生物
肿瘤科
遗传学
组蛋白
基因
组蛋白脱乙酰基酶
作者
Jie Liu,Wei Wang,K Wang,Wenjing Liu,Yanqiu Zhao,Han Xiao,Zhen Li,Bing‐Hua Jiang
标识
DOI:10.1186/s12967-024-05563-3
摘要
The development of acquired EGFR-TKI treatment resistance is still a major clinical challenge in the treatment of non-small cell lung cancer (NSCLC). This study aimed to investigate the role of HDAC1/FOXK1/miR-33a signaling in EGFR-TKI resistance.
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