Cost and Energy Saving Process for the Laboratory-Scale Production of Chloroform-d

Deuterochloroform (CDCl 3 ), a commonly deuterated solvent in research and undergraduate laboratories and widely employed for nuclear magnetic resonance analyses, could be prepared using a more sustainable and efficient catalytic process. The synthesis includes a one-pot reaction of hexachloroacetone with deuterium oxide (D 2 O) in the presence of poly( N -vinylimidazole). The catalyst is more sustainable, highly recyclable, highly chemical and thermally stable, soluble in D 2 O, and high in efficiency.