医学
乳腺癌
免疫疗法
癌症
免疫系统
肿瘤科
生物信息学
内科学
癌症研究
免疫学
生物
作者
Muhammad Luqman Nordin,Ahmad Khusairi Azemi,Normaz Wana Ismail,Abu Hassan Nordin,Walid Nabgan,Nur Amalina Noralidin,Rumaizi Shaari,Nur Zul Izzati Mohd Rajdi,Mohd Farhan Hanif Reduan,Hawa Nordin Siti,Aida Hanum Ghulam Rasool,Nik Nor Izah Nik Ibrahim
出处
期刊:Annals of Animal Science
[De Gruyter]
日期:2023-07-01
卷期号:23 (3): 703-716
标识
DOI:10.2478/aoas-2022-0085
摘要
Abstract Canine mammary carcinoma (CMC) is the most common neoplasm in bitches, and it shares many biological similarities with breast cancer in humans. Drug resistance, high epigenetic mutations, and relapse rates are among the challenges which eventually urge the need for a veterinary oncologist to discover new therapeutic approaches that are more effective and safer. Therefore, in this review, we also cover the current therapeutic strategies from human medicine for the future perspectives of tumor immunotherapy in veterinary medicine. These strategies have great potential to be employed as therapeutic or prophylactic options due to their ability to modulate a specific and potent immune response against CMC. As we acquire a better understanding of canine tumor immunology, we can move towards a brighter prognosis. Additionally, we report on the recent successful studies in breast cancer that may benefit canines as well.
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