On‐Demand Detachable Adhesive Patch with Colorimetric Hydrogel Microdots for Atraumatic Monitoring of Chronic Wounds

Abstract In situ monitoring of chronic wounds requires robust adhesion between adhesives and tissue interfaces. However, the removal of adhesives often results in severe secondary damage to fragile wounds. Here, an on‐demand detachable colorimetric (ODC) patch is reported that combines an asymmetric phase‐transition structure with colorimetric detection hydrogel sites for the atraumatic monitoring of chronic wounds. The asymmetric phase‐transition structure, consisting of a supporting layer and an on‐demand adhesive layer, exhibits excellent flexibility, strong adhesion in both dry and wet conditions, and an adhesion switching ratio exceeding 1200% under a mild temperature stimulus. The embedded, independently distributed hydrogel microdots allow for multiplexed colorimetric monitoring of wound fluids. All functional components are tightly bound together via interfacial interpenetration and hydrosilation reaction. By further integrating with a mobile application, the smart ODC patch enables rapid analysis of detection results, cloud storage, and the generation of clinical treatment recommendations. The integrated strategy synergistically combines critical features within a thin, flexible patch platform, demonstrating significant potential for the atraumatic monitoring of vulnerable tissue wounds.