恩帕吉菲
急性肾损伤
医学
药理学
程序性细胞死亡
二羟基化合物
环境管理计划
细胞损伤
肾
肾脏疾病
细胞凋亡
还原(数学)
心脏病学
泌尿科
麻醉
脂毒性
机制(生物学)
内科学
糖尿病
作者
Chiemi Ema,Takamasa Iwakura,Takayuki Tsuji,Yukihiro Nakayama,Miyu Tsuchida,Atsushi Kitamura,Naoko Katahashi,Sayaka Ishigaki,Shinsuke Isobe,Tomoyuki Fujikura,Naro Ohashi,Akihiko Kato,Ken Sugimoto,Hideo Yasuda
摘要
TG and EMPA attenuate tubular cell death and kidney injury in ferroptosis-mediated AKI models, potentially through the reduction of lipid peroxidation. These findings highlight ferroptosis suppression as a potential mechanism underlying their renoprotective effects in AKI prevention.
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