医学
保持生育能力
生育率
浆液性液体
生殖细胞肿瘤
阶段(地层学)
卵巢癌
观察研究
妇科
疾病
癌症
肿瘤科
外科
内科学
化疗
人口
环境卫生
生物
古生物学
作者
Myriam Gracia,María Alonso-Espías,Ignacio Zapardiel
出处
期刊:Current Opinion in Oncology
[Ovid Technologies (Wolters Kluwer)]
日期:2023-07-06
卷期号:35 (5): 389-393
标识
DOI:10.1097/cco.0000000000000970
摘要
Fertility-sparing surgery in ovarian cancer is an increasing need in gynecology-oncology clinical practice because of the frequent childbearing delay in developed countries. As the evidence in literature is based on observational studies, this review focuses on summarizing the most recent and relevant evidence for the conservative management of young patients with ovarian cancer.Staging surgery is mandatory in epithelial ovarian tumors. In sex cord-stromal tumors, fertility-sparing surgery is only recommended in FIGO stage IA. Due to its good prognosis, conservative treatment is possible in some cases of advanced disease of germ cell tumors and borderline tumors. Cystectomy is a reasonable option in serous borderline tumors but is not recommended in other tumor subtypes. Successful conception rates after fertility-sparing surgery ranges from 30 to 60%.Fertility-sparing surgery is a well tolerated option in young women with early-stage ovarian cancer with acceptable reproductive outcomes.
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