Photoacoustic Tomography to Observe Hemodynamic Changes Induced by Chuanxiong in Mice

Photoacoustic tomography (PAT) was utilized to investigate the hemodynamics effects of Chuanxiong in localized regions of mice. A four-day continuous gavage was administered to healthy mice (n=10), followed by data acquisition using PAT. It was observed that Chuanxiong influenced the concentration of total hemoglobin (HbT) in the brains and legs of mice. These results suggest a consistent impact of Chuanxiong on HbT concentration across various regions in mice, highlighting the potential of PAT in advancing our understanding of the action mechanisms of Chinese herbal medications and enhancing their clinical applications.