摘要
Chapter 40 Pinnipeds (Seals and Sea Lions) James E. Bailey, James E. BaileySearch for more papers by this authorShawn Johnson, Shawn JohnsonSearch for more papers by this author James E. Bailey, James E. BaileySearch for more papers by this authorShawn Johnson, Shawn JohnsonSearch for more papers by this author Book Editor(s):Gary West DVM, DACZM, Gary West DVM, DACZM Senior Vice-president of Animal Health and Living Collections Arizona Center for Nature Conservation/Phoenix ZooSearch for more papers by this authorDarryl Heard BSc, BVMS, DACZM, PhD, Darryl Heard BSc, BVMS, DACZM, PhD Department of Comparative Diagnostic and Population Medicine, College of Veterinary Medicine, University of Florida, Gainesville, FloridaSearch for more papers by this authorNigel Caulkett DVM, MVetSc, DACVAA, Nigel Caulkett DVM, MVetSc, DACVAA VCA Western Veterinary Specialists, Calgary Adjunct Professor University of Calgary Faculty of Veterinary MedicineSearch for more papers by this author First published: 17 January 2025 https://doi.org/10.1002/9781119539278.ch40 AboutPDFPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShareShare a linkShare onEmailFacebookxLinkedInRedditWechat Summary Pinnipeds are a diverse group of aquatic, carnivorous marine mammals that have evolved physically and physiologically to survive and thrive in varied marine environments, often at extremes of temperature, water depth, pressure, and in limited daylight or darkness. Of particular importance to pinniped species is an understanding of the influence of drug choices on breathing and proper ventilatory support. Manual hand ventilation, or controlled mechanical ventilation is the mode of ventilation most often employed for pinnipeds. A voluntary preanesthetic health assessment can provide a general overview of the animal's current health status prior to anesthesia in managed populations where medical behaviors can be cultivated. Behaviors are useful responses taught to pinnipeds by qualified trainers. Tranquilization is the use of pharmacologic agents to promote peace of mind for the subject, such as the anxiolytic effect of the benzodiazepines when delivered alone. Benzodiazepines are very effective in tranquilizing phocids. References Adkesson MJ . 2012 . Reversible immobilization of South American fur seals ( Arctocephalus australis ) and South American sea lions ( Otaria flavescens ) using medetomidine, butorphanol, and midazolam . Proceedings of the International Association for Aquatic Animal Medicine. Google Scholar Adkesson M , Meegan J , Jankowski G , Cárdenas-Alayza S . 2013 . Evaluation of alfaxalone (Alfaxan®) for sedation of South American fur seals ( Arctocephalus australis ) . Proceedings of the International Association for Aquatic Animal Medicine. Google Scholar Adkesson MJ , Chinnadurai SK , Balko JA , Jankowski G , Meegan JM , Cárdenas-Alayza S , Allender MC . 2019 . Anesthesia of free-ranging Peruvian fur seals ( Arctocephalus australis ) using medetomidine, midazolam and butorphanol . Proceedings of the Zoo and Wildlife Health Conference , pp. 57 – 58 . Google Scholar Bailey J. 2013 . Arterial blood pressure monitoring of select pinnipeds: multi-case presentation . Proceedings of the International Association for Aquatic Animal Medicine. Google Scholar Bailey J , Flanagan C , Meegan J , et al. 2012 . Cogent evidence of rhabdomyolysis in a California sea lion ( Zalophus californianus ) and a South African fur seal ( Arctocephalus pusillus pusillus ) during anesthesia . Proceedings of International Association for Aquatic Animal Medicine. Google Scholar Bailey J , Ridgway S . 2020 . Anesthesia ventilator for Atlantic bottlenose dolphins and California sea lions . Navy STTR FY2014A – Topic N14A–T015 . Office of Naval Research . Google Scholar Bailey JE , Pablo LS . 1998 . Practical approach to acid-base disorders . The Veterinary Clinics of North America: Small Animal Practice 28 : 645 – 662 . 10.1016/S0195-5616(98)50060-5 CASPubMedWeb of Science®Google Scholar Baker JR , Anderson SS , Fedak MA . 1988 . The use of a ketamine–diazepam mixture to immobilize wild gray seals ( Halichoerus grypus ) and southern elephant seals ( Mirounga leonina ) . The Veterinary Record 123 : 287 – 289 . 10.1136/vr.123.11.287 CASPubMedWeb of Science®Google Scholar Baker JR , Fedak MA , Anderson SS , Arnbom T , Baker R . 1990 . Use of a tiletamine-zolazepam mixture to immobilise wild grey seals and southern elephant seals . The Veterinary Record 126 ( 4 ): 75 – 77 . CASPubMedGoogle Scholar Barnett J. 1998 . Treatment of sick and injured marine mammals . In Practice 20 ( 4 ): 200 – 211 . 10.1136/inpract.20.4.200 Web of Science®Google Scholar Bednarski R. 1991 . Anesthesia equipment . In: Equine Anesthesia: Monitoring and Emergency Therapy ( WW Muir , JAE Hubbell , eds.). St. Louis : Mosby Year Book . Google Scholar Berta A , Churchill M , Boessenecker R . 2018 . The origin and evolutionary biology of pinnipeds: seals, sea lions, and walruses . Annual Review of Earth and Planetary Sciences 46 : 203 – 228 . 10.1146/annurev-earth-082517-010009 CASWeb of Science®Google Scholar Bester MN . 1988 . Chemical restraint of Antarctic fur seals and southern elephant seals . South African Journal of Wildlife Research 18 ( 2 ): 57 – 60 . Google Scholar Bodley K , Petel TVP , Gales N . 2005 . Immobilisation of free-living Weddell seals Leptonychotes weddellii using midazolam and isoflurane . Polar Biology 28 : 631 – 636 . 10.1007/s00300-005-0725-6 Web of Science®Google Scholar Boyd IL , Lunn NJ , Duck CD , Barton T . 1990 . Response of Antarctic fur seals to immobilization with ketamine, ketamine-diazepam or ketamine-xylazine mixture, and Zoletil® . Marine Mammal Science 6 ( 2 ): 135 – 145 . 10.1111/j.1748-7692.1990.tb00235.x Web of Science®Google Scholar Brosnan RJ , Eger EI 2nd , Laster MJ , Sonner JM . 2007 . Anesthetic properties of carbon dioxide in the rat . Anesthesia and Analgesia 105 : 103 – 106 . 10.1213/01.ane.0000265556.69089.78 CASPubMedWeb of Science®Google Scholar Brunson DB . 2015 . Comparative anesthesia and analgesia of aquatic mammals . In: Veterinary Anesthesia and Analgesia , 5th ed. ( S Robertson , L Lamont , WJ Tranquilli , K Grimm , SA Greene , eds.). Wiley and Sons . 10.1002/9781119421375.ch41 Google Scholar Bukoski A , Hodgson D , Downs J , Lebert C , Thombs L , Bailey J . 2022 . An implementation of apneustic anesthesia ventilation in the horse: comparison with conventional mechanical ventilation . Veterinary Anaesthesia and Analgesia 49 : 372 – 381 . 10.1016/j.vaa.2022.04.002 CASPubMedWeb of Science®Google Scholar Carlini AR , Negrete J , Daneri GA , Rogers T , Márquez MEI , Ciaglia M , Mennucci JA . 2009 . Immobilization of adult male southern elephant seals ( Mirounga leonina ) during the breeding and molting periods using a tiletamine/zolazepam mixture and ketamine . Polar Biology 32 : 915 – 921 . 10.1007/s00300-009-0592-7 Web of Science®Google Scholar Champagne CD , Houser DS , Costa DP , Crocker DE . 2012 . The effects of handling and anesthetic agents on the stress response and carbohydrate metabolism in northern elephant seals . PloS One 7 ( 5 ): e38442 . 10.1371/journal.pone.0038442 CASPubMedWeb of Science®Google Scholar Coghlan M , Richards E , Shaik S , Rossi P , Vanama RB , Ahmadi S , Petroz C , Crawford M , Maynes JT . 2018 . Inhalational anesthetics induce neuronal protein aggregation and affect ER trafficking . Scientific Reports 8 : 5275 . 10.1038/s41598-018-23335-0 PubMedWeb of Science®Google Scholar Colitz CMH , Bailey JE . 2019 . Lens diseases and anesthetic considerations for ophthalmologic procedures in pinnipeds . In: Fowler's Zoo and Wild Animal Medicine Current Therapy , Vol. 9 ( RE Miller , N Lamberski , PP Calle , eds.), pp. 610 – 617 . St. Louis : Elsevier . 10.1016/B978-0-323-55228-8.00086-2 Google Scholar Corkeron P. 2009 . Captivity . In: Encyclopedia of Marine Mammals , 2nd ed. ( B Wursig , JGM Thewissen , K Kovacs , eds.), Academic Press , Cambridge Massachusetts, USA , pp. 183 – 188 . 10.1016/B978-0-12-373553-9.00049-3 Google Scholar Dabin W , Beauplet G , Guinet C . 2002 . Response of wild subantarctic fur seal ( Arctocephalus tropicalis ) females to ketamine and tiletamine-zolazepam anesthesia . Journal of Wildlife Diseases 38 ( 4 ): 846 – 850 . 10.7589/0090-3558-38.4.846 PubMedGoogle Scholar David JHM , Hofmeyr JM , Best PB , Meyer MA , Shaughnessy PD . 1988 . Chemical immobilization of free-ranging South African (Cape) fur seals . South African Journal of Wildlife Research 18 : 154 – 156 . Web of Science®Google Scholar Davis RW , Castellini MA , Kooyman GL , Maue R . 1983 . Renal glomerular filtration rate and hepatic blood flow during voluntary diving in Weddell seals . American Journal of Physiology – Regulatory, Integrative and Comparative Physiology 245 : R743 – R748 . 10.1152/ajpregu.1983.245.5.R743 CASPubMedWeb of Science®Google Scholar Denison D , Warrell DA , West JB . 1972 . Airway structure and alveolar emptying in the lungs of sea lions and dogs . Respiration Physiology 13 : 253 – 261 . 10.1016/0034-5687(71)90029-6 Google Scholar Dennison S , Haulena M , Williams DC , Dawson J , Yandell BS , Gulland FM . 2008 . Determination of a sedative protocol for use in California sea lions ( Zalophus californianus ) with neurologic abnormalities undergoing electroencephalographic examination . Journal of Zoo and Wildlife Medicine 39 ( 4 ): 542 – 547 . 10.1638/2007-0077.1 PubMedGoogle Scholar Dubreuil V , Barhanin J , Goridis C , Brunet J-F . 2009 . Breathing with Phox2b . Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences 364 : 2477 – 2483 . 10.1098/rstb.2009.0085 CASPubMedWeb of Science®Google Scholar Eisele JH , Eger EI , Muallem M . 1967 . Narcotic properties of carbon dioxide in the dog . Anesthesiology 28 : 856 – 865 . 10.1097/00000542-196709000-00019 CASPubMedWeb of Science®Google Scholar Elsner R , Franklin DL , Van Citters RL , Kenney DW . 1966 . Cardiovascular defense against asphyxia . Science 153 : 941 – 949 . 10.1126/science.153.3739.941 CASPubMedWeb of Science®Google Scholar Fahlman A , Loring SH , Ferrigno M , Moore C , Early G , Niemeyer M , Lentell B , Wenzel F , Joy R , Moore MJ . 2011 . Static inflation and deflation pressure–volume curves from excised lungs of marine mammals . Journal of Experimental Biology 214 : 3822 – 3828 . 10.1242/jeb.056366 PubMedWeb of Science®Google Scholar Ferreira SM , Bester MN . 1999 . Chemical immobilization, physical restraint and stomach lavaging of fur seals at Marion Island . South African Journal of Wildlife Research 29 ( 3 ): 55 – 61 . Google Scholar Folkow LP , Nordøy ES , Blix AS . 2010 . Remarkable development of diving performance and migrations of hooded seals ( Cystophora cristata ) during their first year of life . Polar Biology 33 : 433 – 441 . 10.1007/s00300-009-0718-y Google Scholar Fourcade HE , Stevens WC , Larson CP Jr , Cromwell TH , Bahlman SH , Hickey RF , Halsey MJ , Eger EI 2nd . 1971 . The ventilatory effects of Forane, a new inhaled anesthetic . Anesthesiology 35 : 26 – 31 . 10.1097/00000542-197107000-00008 CASPubMedWeb of Science®Google Scholar Frankfurter G , DeRango E , Johnson S . 2016 . Use of acoustic transmitter-equipped remote sedation to aid in tracking and capture of entangled California sea lions ( Zalophus californianus ) . Journal of Wildlife Diseases 52 ( 3 ): 730 – 733 . 10.7589/2015-10-274 PubMedWeb of Science®Google Scholar Gage LJ , Gerber JA , Smith DM , Morgan LE . 1993 . Rehabilitation and treatment success rate of California sea lions ( Zalophus californianus ) and northern fur seals ( Callorhinus ursinus ) stranded along the central and northern California coast, 1984–1990 . Journal of Zoo and Wildlife Medicine 24 ( 1 ): 41 – 47 . Web of Science®Google Scholar Gales NJ , Mattlin RH . 1998 . Fast, safe, field-portable gas anesthesia for otariids . Marine Mammal Science 14 ( 2 ): 355 – 361 . 10.1111/j.1748-7692.1998.tb00727.x Web of Science®Google Scholar Gales N , Barnes J , Chittic B , Gray M , Robinson S , Burns J , Costa D . 2005 . Effective, field-based inhalation anesthesia for ice seals . Marine Mammal Science 21 ( 4 ): 717 – 727 . 10.1111/j.1748-7692.2005.tb01261.x Web of Science®Google Scholar Gardner BR , Spolander B , Mduduzi Seakamela S , McCue SA , Kotze PG , Musson M . 2021 . Disentanglement of Cape fur seals ( Arctocephalus pusillus pusillus ) with reversible medetomidine-midazolam-butorphanol . Journal of the South African Veterinary Association 92 ( 1 ): 1 – 5 . Google Scholar Geschke K , Chilvers BL . 2009 . Managing big boys: a case study on remote anaesthesia and satellite tracking of adult male New Zealand sea lions ( Phocarctos hookeri ) . Wildlife Research 36 ( 8