嗜酸性食管炎
医学
免疫疗法
口服免疫疗法
免疫病理学
皮肤病科
食管炎
免疫学
过敏
胃肠病学
内科学
疾病
免疫系统
回流
作者
Bridget E. Wilson,Maria A. Sacta,Benjamin L. Wright,Jonathan M. Spergel,Nicole Wolfset
标识
DOI:10.1016/j.iac.2024.01.001
摘要
Immunotherapy is a treatment approach based on the principle of incremental allergen exposure to achieve desensitization. Recently, oral immunotherapy has been introduced as a treatment of IgE-mediated food allergy. Some patients receiving oral immunotherapy for food allergy may develop eosinophilic esophagitis. Here, we summarize the literature examining this association, its treatment, and outcomes and discuss possible explanations for this clinical phenomenon. We further identify potential associations with aeroallergen sensitivity and other forms of immunotherapy including subcutaneous immunotherapy and sublingual immunotherapy. Finally, we discuss management of immunotherapy-induced eosinophilic esophagitis. Epicutaneous immunotherapy is highlighted as an area of therapeutic investigation.
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