Application of Benzoylaceteonitrile in the Synthesis of Pyridines Derivatives

This review deals with synthetic potential and utility of benzoylacetonitrile in the synthesis of pyridine derivatives. The reac- tions are subdivided into groups that cover the synthetic methods of pyridine derivatives from benzoylacetonitrile e.g. self condensation, Friedlander reaction, Michael Addition reaction, addition to enaminones, reaction with enamino-nitriles or enamino-esters, and one-pot three component reactions. A brief account on the synthesis of benzoylacetonitrile was also displayed.