CONVENIENT SYNTHESIS OF 1-AZA-3-THIABICYCLO[3.1.0]HEXANES FROM L-CYSTEINE

Abstract Synthesis of optically active 2-substituted and unsubstituted 1-aza-3-thiabicyclo[3,1.0]hexanes are accomplished By intramolecular cyclization of 4-hydroxymethylthiazolidines which are prepared By the reaction of l-cysteine methyl ester with appropriate aldehydes followed By reduction of ester function.