Effects of somatostatin in treating acute pancreatitis

AIM:To observe the effects of somatostatin in treating acute pancreatitis.METHODS:The somatostatin group including 8 patients with acute edematic pancreatitis(AEP) and 12 patients with acute severe pacreatitis (ASP) received a 3-7day infusion of somatostatin(250μg/h).The control group including 8 patients with AEP and 12 patients with ASP was treated without somatostatin. The severities were similar between the two groups according to APACHE Ⅱ scores. RESULTS:The treating outcomes of the two groups were compard.The duration of the return of serum amylase levels to normal and hospital stay of somatostatin group with ASP were less than those of the control group with ASP significantly (P0.05).But there was no significant difference between the two groups with AEP(P0.05).CONCLUSION:Somatostatin exerted its beneficial effects in treating ASP.