Research Progress of Pyrroloquinoline-quinone

Pyrroloquinoline quinone(PQQ) was discovered as a new kind of coenzyme for oxidoreductase at the end of 1970s.PQQ occurs in nature in some dehydrogenases present in certain gram-negative bacteria.The distinct structure of the compound make it differ from the normal cofactor NAD(P) and FMN、FAD,and play an important role in biological functions.There are two structural types of PQQ-containing enzymes.The one that contains PQQ only in the active site is referred to as quinoproteins.Other group of enzymes-containing PQQ and one or more heme groups are known as quino-hemo-proteins.To introduce its properties,sources,function and the research progress of PQQ synthetic biology gene.To point out that the developrent of researching PQQ continuously medicine industrial production,agriculture will be promoted through.