TWIST1 ‐Mediated Induction of AEBP1 in Fibroblast‐Like Synoviocytes Activates Transforming Growth Factor β Signaling to Drive Angiogenesis and Promote Rheumatoid Arthritis

Our study suggests that POSTN⁺ FLS located in the synovial sublining contribute to RA progression through the TWIST1-AEBP1-POSTN axis. Accordingly, targeting of this axis may offer a novel and effective approach for RA treatment.