微生物群
生物
粪便细菌疗法
失调
肝移植
移植
人类微生物组计划
代谢物
粪便
肠道微生物群
免疫学
队列
内科学
生物信息学
微生物学
艰难梭菌
人体微生物群
医学
抗生素
内分泌学
作者
Angélica T. Vieira,Thomas F. Baumert
标识
DOI:10.1016/j.chom.2023.12.005
摘要
In this issue, Lehmann et al. addresses the high infection risk in liver transplantation by examining the gut microbiome in a patient cohort. By uncovering a predictive role of the microbiome for the clinical course, the study unravels the gut microbiome as a guidepost for infection risk in liver transplantation. In this issue, Lehmann et al. addresses the high infection risk in liver transplantation by examining the gut microbiome in a patient cohort. By uncovering a predictive role of the microbiome for the clinical course, the study unravels the gut microbiome as a guidepost for infection risk in liver transplantation. Fecal metabolite profiling identifies liver transplant recipients at risk for postoperative infectionLehmann et al.Cell Host & MicrobeDecember 15, 2023In BriefLehmann and colleagues link fecal metabolite concentrations with infections in liver transplant recipients. Decreased short-chain fatty acid, secondary bile acids, and other microbially derived metabolite concentrations are associated with intestinal pathobiont expansion and postoperative infections. Specification of intestinal dysbiosis by fecal metabolite quantitation may provide approaches to target microbiome reconstitution. Full-Text PDF
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