In silico design of novel potential isonicotinamide-based glycogen synthase kinase-3β (GSK-3β) inhibitors: 3D-QSAR, molecular docking, molecular dynamics simulation and ADMET studies

GSK-3β is a highly sought-after target in drug development and its inhibitors are potential candidates for various diseases. Isonicotinamide derivatives have been proven to be promising leads for GSK-3β inhibitor...