Deep in situ pressure coring provides an accurate means of determining oil and gas reserve parameters. The key to achieving pressure coring at depths exceeding 5000 m lies in the ultimate bearing strength and stability of the pressure controllers. Due to the limited downhole space and the inherent technical demands of pressure coring, traditional pressure coring technology typically has an ultimate bearing pressure capacity of less than 70 MPa. The structural model of the pressure controller is designed. The stress–strain distribution of the pressure controller under external load is numerically simulated. A contact stress optimization scheme and critical sealing gap of pressure controllers are proposed. It was found that the saddle pressure controllers can ensure the fit clearance of the sealing surface and effectively control the deformation of the valve cover within 0.015 mm. The saddle pressure controllers have demonstrated an ultimate bearing strength exceeding 140 MPa, with minimal leakage. These findings have significant implications for accurate assessment of deep petroleum resources.