组胺能
组胺
神经科学
组胺受体
神经元回路
组胺H3受体
受体
生物
药理学
敌手
生物化学
作者
Zhong Chen,Lingyu Xu,Wenkai Lin,Yanrong Zheng,Yi Wang
出处
期刊:Current Neuropharmacology
[Bentham Science]
日期:2024-02-01
卷期号:22 (2): 241-259
被引量:1
标识
DOI:10.2174/1570159x21666221117153755
摘要
Feeding is an intrinsic and important behavior regulated by complex molecular, cellular and circuit-level mechanisms, one of which is the brain histaminergic network. In the past decades, many studies have provided a foundation of knowledge about the relationship between feeding and histamine receptors, which are deemed to have therapeutic potential but are not successful in treating feeding- related diseases. Indeed, the histaminergic circuits underlying feeding are poorly understood and characterized. This review describes current knowledge of histamine in feeding at the receptor level. Further, we provide insight into putative histamine- involved feeding circuits based on the classic feeding circuits. Understanding the histaminergic network in a circuit-specific way may be therapeutically relevant for increasing the drug specificity and precise treatment in feeding-related diseases.
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