炎症
神经炎症
医学
脊髓损伤
病态的
炎症反应
脊髓
神经科学
生物信息学
免疫学
病理
心理学
生物
精神科
作者
Ximena Freyermuth-Trujillo,Julia J. Segura-Uribe,Hermelinda Salgado‐Ceballos,Carlos E. Orozco-Barrios,Angélica Coyoy-Salgado
出处
期刊:Cells
[MDPI AG]
日期:2022-08-29
卷期号:11 (17): 2692-2692
被引量:36
标识
DOI:10.3390/cells11172692
摘要
Spinal cord injury (SCI) is a significant cause of disability, and treatment alternatives that generate beneficial outcomes and have no side effects are urgently needed. SCI may be treatable if intervention is initiated promptly. Therefore, several treatment proposals are currently being evaluated. Inflammation is part of a complex physiological response to injury or harmful stimuli induced by mechanical, chemical, or immunological agents. Neuroinflammation is one of the principal secondary changes following SCI and plays a crucial role in modulating the pathological progression of acute and chronic SCI. This review describes the main inflammatory events occurring after SCI and discusses recently proposed potential treatments and therapeutic agents that regulate inflammation after insult in animal models.
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