催化作用
化学
亲核取代
激活剂(遗传学)
替代(逻辑)
酒
组合化学
亲核加成
有机化学
亲核细胞
药物化学
计算机科学
程序设计语言
生物化学
基因
作者
Christine M. Vanos,Tristan H. Lambert
标识
DOI:10.1002/anie.201104638
摘要
Cyclopropenone makes the switch: 2,3-Bis-(p-methoxyphenyl)cyclopropenone is a highly efficient catalyst for the chlorodehydration of 20 diverse alcohol substrates (see scheme; X=Cl). With oxalyl chloride as catalytic activator, this nucleophilic substitution proceeded through cyclopropenium-activated intermediates and resulted in complete stereochemical inversion in substrates with chiral centers. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
科研通智能强力驱动
Strongly Powered by AbleSci AI