医学
内科学
肿瘤科
化疗
养生
长春瑞滨
中性粒细胞减少症
耐火材料(行星科学)
拓扑替康
发热性中性粒细胞减少症
吉西他滨
依托泊苷
蒽环类
噻替帕
挽救疗法
化疗方案
临床研究阶段
胃肠病学
长春新碱
作者
Prashant Hiwarkar,H. T Arkenau,Jennifer Treleaven,Gareth J. Morgan,Michael Potter,Mark Ethell
出处
期刊:Leukemia
[Springer Nature]
日期:2008-02-28
卷期号:22 (8): 1627-1629
被引量:3
摘要
The success of haematopoietic stem cell transplantation depends upon the pretransplant leukaemic burden.1 In relapsed or refractory acute leukaemia and high-grade non-Hodgkin's lymphoma, the main aim is to decrease the leukaemic cell population to submicroscopic level so that consolidation with haematopoietic stem cell transplantation can be performed. In these heavily pretreated patients, there are issues of development of drug resistance and further risk of comorbidities from salvage chemotherapy. Thus for prolonged survival of such patients, a protocol that can induce disease remission to last long enough to perform haematopoietic stem cell transplantation and also prevent vital organ dysfunction is required.
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