亲爱的研友该休息了!由于当前在线用户较少,发布求助请尽量完整的填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!身体可是革命的本钱,早点休息,好梦!

Degradation of Multiple Peptides by Microcystin-Degrader Paucibacter toxinivorans (2C20)

微囊藻毒素 微囊藻毒素 生物降解 化学 降级(电信) 蓝藻 细菌 铜绿微囊藻 色谱法 生物化学 生物 有机化学 计算机科学 遗传学 电信
作者
Allan Amorim Santos,Sylvia Soldatou,Valéria Freitas de Magalhães,Sandra M. F. O. Azevedo,Dolores Camacho‐Muñoz,Linda A. Lawton,Christine Edwards
出处
期刊:Toxins [Multidisciplinary Digital Publishing Institute]
卷期号:13 (4): 265-265 被引量:16
标识
DOI:10.3390/toxins13040265
摘要

Since conventional drinking water treatments applied in different countries are inefficient at eliminating potentially toxic cyanobacterial peptides, a number of bacteria have been studied as an alternative to biological filters for the removal of microcystins (MCs). Here, we evaluated the degradation of not only MCs variants (-LR/DM-LR/-RR/-LF/-YR), but also non-MCs peptides (anabaenopeptins A/B, aerucyclamides A/D) by Paucibactertoxinivorans over 7 days. We also evaluated the degradation rate of MC-LR in a peptide mix, with all peptides tested, and in the presence of M. aeruginosa crude extract. Furthermore, biodegradation was assessed for non-cyanobacterial peptides with different chemical structures, such as cyclosporin A, (Glu1)-fibrinopeptide-B, leucine-enkephalin, and oxytocin. When cyanopeptides were individually added, P. toxinivorans degraded them (99%) over 7 days, except for MC-LR and -RR, which decreased by about 85 and 90%, respectively. The degradation rate of MC-LR decreased in the peptide mix compared to an individual compound, however, in the presence of the Microcystis extract, it was degraded considerably faster (3 days). It was noted that biodegradation rates decreased in the mix for all MCs while non-MCs peptides were immediately degraded. UPLC–QTOF–MS/MS allowed us to identify two linear biodegradation products for MC-LR and MC-YR, and one for MC-LF. Furthermore, P. toxinivorans demonstrated complete degradation of non-cyanobacterial peptides, with the exception of oxytocin, where around 50% remained after 7 days. Thus, although P. toxinivorans was previously identified as a MC-degrader, it also degrades a wide range of peptides under a range of conditions, which could be optimized as a potential biological tool for water treatment.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
qiuqiutantan发布了新的文献求助10
2秒前
科研通AI5应助qiuqiutantan采纳,获得10
12秒前
科研通AI5应助天真的雁露采纳,获得10
16秒前
20秒前
李健的粉丝团团长应助guan采纳,获得10
56秒前
烟花应助andrele采纳,获得10
1分钟前
滴滴滴完成签到 ,获得积分10
1分钟前
wodetaiyangLLL完成签到 ,获得积分10
1分钟前
1分钟前
1分钟前
oleskarabach发布了新的文献求助10
1分钟前
品如的文献完成签到,获得积分10
1分钟前
1分钟前
1分钟前
tutu完成签到,获得积分10
1分钟前
qiuqiutantan发布了新的文献求助10
1分钟前
大模型应助科研通管家采纳,获得10
1分钟前
星辰大海应助qiuqiutantan采纳,获得10
1分钟前
李爱国应助oleskarabach采纳,获得10
1分钟前
梦红完成签到,获得积分10
1分钟前
牙线棒棒哒完成签到 ,获得积分10
1分钟前
2分钟前
yuan完成签到 ,获得积分10
2分钟前
2分钟前
2分钟前
oleskarabach发布了新的文献求助10
2分钟前
科研通AI5应助甜美帅哥采纳,获得10
2分钟前
2分钟前
斯文败类应助pokikiii采纳,获得10
2分钟前
2分钟前
2分钟前
紫翼应助wafo采纳,获得10
2分钟前
甜美帅哥发布了新的文献求助10
2分钟前
Linden_bd完成签到 ,获得积分10
2分钟前
甜美帅哥完成签到,获得积分10
3分钟前
难过板栗完成签到,获得积分20
3分钟前
西吴完成签到 ,获得积分10
3分钟前
3分钟前
慕青应助鲜于夜白采纳,获得10
3分钟前
qiuqiutantan发布了新的文献求助10
3分钟前
高分求助中
Encyclopedia of Mathematical Physics 2nd edition 888
Chinesen in Europa – Europäer in China: Journalisten, Spione, Studenten 500
Arthur Ewert: A Life for the Comintern 500
China's Relations With Japan 1945-83: The Role of Liao Chengzhi // Kurt Werner Radtke 500
Two Years in Peking 1965-1966: Book 1: Living and Teaching in Mao's China // Reginald Hunt 500
材料概论 周达飞 ppt 500
Nonrandom distribution of the endogenous retroviral regulatory elements HERV-K LTR on human chromosome 22 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 物理 生物化学 纳米技术 计算机科学 化学工程 内科学 复合材料 物理化学 电极 遗传学 量子力学 基因 冶金 催化作用
热门帖子
关注 科研通微信公众号,转发送积分 3808017
求助须知:如何正确求助?哪些是违规求助? 3352716
关于积分的说明 10360009
捐赠科研通 3068716
什么是DOI,文献DOI怎么找? 1685237
邀请新用户注册赠送积分活动 810332
科研通“疑难数据库(出版商)”最低求助积分说明 766033