Intraoperative spectrally encoded coherence tomography and reflectometry (iSECTR) for ophthalmic surgical guidance

Intraoperative optical coherence tomography (iOCT) has enabled depth-resolved intraoperative imaging of retinal microstructures. Despite recent advancements, iOCT of surgical maneuvers remains challenging because the imaging field-of-view requires manual adjustment and tracking. To overcome this limitation, we previously demonstrated spectrally encoded coherence tomography and reflectometry (SECTR), which provides OCT imaging and a complementary en face view for visualization of surgical instruments and tool-tracking. Here, we demonstrate ophthalmic imaging with an intraoperative SECTR (iSECTR) system integrated with a surgical microscope. We believe that iSECTR will allow for real-time feedback on the location and depth of surgical instruments to better guide ophthalmic surgery.