聚己二酮
极限抗拉强度
材料科学
食管支架
支架
芯(光纤)
粘附
生物医学工程
延伸率
复合材料
外科
医学
作者
Cheol-Min Han,Eugene Lih,Seongjin Choi,Tarek M. Bedair,Young Jae Lee,Wooram Park,Dong Keun Han,Jun Sik Son,Yoon Ki Joung
标识
DOI:10.1016/j.jiec.2018.07.014
摘要
In this study, a polydioxanone (PDO) and poly(L-lactic acid) (PLLA) sheath-core biphasic monofilament was designed to develop an esophageal stent with improved mechanical properties and controlled biodegradability. The radial force of PDO/PLLA sheath-core stent was 10.24 N, while that of PDO stent was 5.64 N. Deteriorations of tensile strength, elastic modulus and elongation during degradation test were also delayed on PDO/PLLA group. Hyaluronic acid–dopamine conjugate and BaSO4/PDO conjugate coating layers provided improved tissue adhesion strength and reasonable X-ray contrast, respectively. Taken all together, the sheath-core filaments with tissue adhesive and radiopaque properties will be useful in designing esophageal stents.
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