Using the method of modeling addition indoor, the sensitivity of sulfonylurea herbicideS to mai2e was studied. In addition, with the method of planting in pot, the effect of sulfonylurea herbicides to maize in seedling was observed.Finally,with bioassay method, the residue dynamics of sulfonylurea herbicides in wheat soil was detected. The results showed that there were different sensitivities to sulfonylurea herbicides among different maize varieties. The concentration of three kinds of sulfonylurea herbicides beyond ED10 hadan obvious effect on length of roots, height of plant,area of leaves in maize seedling. In the residue dynamics test in wheat soil, the residue time of sulfometuron-methyl is the longest; bensulfuron-methyl,the second;tribenuron-methyl,the shortest.