Research Progress of Survivin in Gynecologic Tumors

Survivin is a new member of the apoptosis protein inhibitors family,the function of which is to inhibit the cell apoptosis and regulate the cell mitosis process. Survivin is a very important factor to connect the cell cycle and apoptosis process. The over expression of survivin in the tissue can inhibit the cell apoptosis. Survivin is also involved in the cell division and multiplication. Survivin depends on the cell cycle procedure strictly. Many studies indicated that survivin expressed widely in many kinds of human tumors,indicating its important roles in the apoptosis of tumor cells. The studies in recent years revealed that survivin had been concerned in the genesis,development,and prognosis of gynecologic tumors closely. As the new target,survivin will bring a new breakthrough for the gene diagnosis and treatment of gynecologic tumors.