后代
生物
粪便
断奶
拟杆菌
生理学
回肠
动物科学
怀孕
微生物学
内分泌学
细菌
遗传学
16S核糖体RNA
作者
Ursula M. McCormack,Tânia Curião,Toby Wilkinson,Barbara U. Metzler-Zebeli,Henry Reyer,Tomás Ryan,Julia A. Calderon-Diaz,Fiona Crispie,Paul D. Cotter,Christopher J. Creevey,Gillian E. Gardiner,Peadar G. Lawlor
出处
期刊:MSystems
[American Society for Microbiology]
日期:2018-03-13
卷期号:3 (3)
被引量:66
标识
DOI:10.1128/msystems.00134-17
摘要
Here, for the first time, we investigate FMT as a novel strategy to modulate the porcine intestinal microbiota in an attempt to improve FE in pigs. However, reprogramming the maternal and/or offspring microbiome by using fecal transplants derived from highly feed-efficient pigs did not recapitulate the highly efficient phenotype in the offspring and, in fact, had detrimental effects on lifetime growth. Although these findings may not be wholly attributable to microbiota transplantation, as antibiotic and purgative were also part of the regime in sows, similar effects were also seen in offspring, in which these interventions were not used. Nonetheless, additional work is needed to unravel the effects of each component of the FMT regime and to provide additional mechanistic insights. This may lead to the development of an FMT procedure with practical applications for the improvement of FE in pigs, which could in turn improve the profitability of pig production.
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